Multiverse Pharma | Precision Biotherapeutics for Complex Disease

Multiverse Pharma Inc.

Cross Barriers | Reach the Brain

Novel brain shuttle for CNS therapies

Available for licensing and collaboration

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MVP-104 BBB Shuttle: The Gateway To CNS Drug Delivery

Contact Multiverse Pharma for more information on MVP-104, a shuttle targeting IGF-1R which safely and effectively delivers therapeutic cargo to the brain

All data validated in non-human primates

Highly specific IGF-1R targeting with no receptor activation or peripheral sink
Sustained brain exposure after single IV dose
High levels of unbound drug in brain parenchyma enabling bioavailability
Broad, uniform distribution across key brain regions
Minimal vascular retention and negligible CSF clearance
Modular plug-and-play platform compatible with diverse therapeutic cargoes

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MVP Fc-Heterodimerization

Unlock drug-shuttle fusion flexibility and scalability

High protein yields
Improved stability
Reduced by-product formation
De-immunized Fc for safety
Robust and ready for a variety of payloads

Combining MVP-104 with our Fc-heterodimerization platform enables precise and customizable targeting strategies

Technology and Development Pipeline

Leadership Team

Jeonghoon Sun, PhD

Founder & Chief Executive

20+ years of industry research experience
Principal and leadership roles at Amgen, Eli Lilly, Celgene, and Alector
8 clinical stage molecules
50+ published patents and research papers
Post-Doctoral Fellow, Protein Engineering (University of California, San Francisco & United States Department of Defense)
Ph.D Chemistry (State University of New York, Stony Brook)

Brydon Bennett, PhD

Chief Scientific Officer

30+ years of inflammation & immunology research experience;
A leader in drug discovery
20 year career at Celgene
5 clinical stage molecules
75+ published patents and research papers
Post-Doctoral Fellow, NF-kB pathways (The Upjohn Company)
Ph.D Biochemistry and Molecular Biology (University of Otago, NZ)

Advisory Board

Gregory Reyes, MD-PhD

Scientific Advisor

30+ years of leadership in Drug Discovery (Celgene, Biogen, Pfizer, Schering-Plough)
50+ drug molecules nominated to preclinical and clinical study
2012 Prix Galien Award by Victrelis™
150+ published patents and research literature

Nicole Sampson, PhD

Scientific Advisor

Provost & Chief Academic Officer (University of Rochester)
Former Distinguished Professor & Dean (College of Arts and Sciences, State University of New York, Stony Brook)
American Chemical Society Fellow